Yes, usually. Drop-Off/Set-Up is where the Owner takes the vehicle to a holiday location for a hirer (And is not movable by the hirer).
We refer to this as the "Relocation Fee" which is added to the booking cost by the owner before approving the booking and after discussing with the hirer.
Be mindful that some owners will only allow their vehicle to be towed/driven by the hirer, and Drop-Off/Set-Up may not be available. Others may include an extra charge for taking the van to your desired location (for example, the airport, where you can start or end your holiday). You can check this via the Hire Options/Additional Products listed against the vehicle you're looking at.